Plant transposons

Plant transposons


We are studying the interactions between proteins encoded by the maize Suppressor-mutator (Spm) and transposon DNA sequences using purified proteins expressed in bacteria and insect cells.  Our eventual objectives are also to understand the mechansisms underlying the epigenetic regulation of maize transposons.


This research is in collaboration with Dr. Samir Hamdan at KAUST


  • Cui, H., and Fedoroff, N. V. (2002) Inducible DNA demethylation mediated by the maize Spm transposon-encoded TnpA protein.  Plant Cell 14:1-17.   PDF 
  • Schäppi, M., Karunananandaa, B., Elhofy, A. and Fedoroff, N. (1998). Concerted formation of macromolecular Spm transposition complexes.  Proc. Natl. Acad. Sci USA 95: 8526-8531. PDF
  • Fedoroff, N. V., Schläppi, M., and Raina, R. (1995).  Epigenetic regulation of the maize Spm transposon.  Bioessays 17, 291-297.  PDF