The Fedoroff group has interests ranging from the molecular mechanism of microRNA processing, to epigenetic regulation of transposons and abiotic stress responses, to the development of new halophytic crops and salt-tolerant varieties of existing crops, and new greenhouse designs suitable for coastal desert conditions of high temperature and humidity. Fedoroff is the Director of KAUST's Center for Desert Agriculture CDA as well as organizer of KAUST's Desert Agriculture Research Initiative (DARI), a collaborative effort involving several of KAUST's research centers, individuals in other universities (both in Saudi Arabia and other countries), companies and both governmental and non-governmental organizations.